⚠️ Educational purposes only. PeptideIQ does not constitute medical advice, diagnosis, or treatment. Peptide therapy should only be pursued under the guidance of a licensed medical provider. Many peptides discussed are research-grade compounds not approved by the FDA. Always verify current legal status in your jurisdiction before use.
← Back to library
MOTS-c
Mitochondrial Open Reading Frame of the 12S rRNA-c
PreclinicalResearch Grade
A mitochondria-derived peptide that regulates metabolic homeostasis, exercise response, and systemic aging.
Mechanism of action
AMPK activation, mitochondrial biogenesis, metabolic regulation, insulin sensitivity
Primary benefits
- ✓Metabolic health
- ✓Exercise performance
- ✓Insulin sensitivity
- ✓Longevity signaling
- ✓Fat metabolism
Dosing
Beginner
5 mg 2-3x weekly
Intermediate
10 mg 2-3x weekly
Advanced
10-15 mg 3x weekly
Frequency: 2-3x per week
Timing: Pre-workout or morning
Route: Subcutaneous injection
Cycling protocol
Duration
8-12 weeks
Pattern
3x weekly
Break after
4-6 weeks
Important warnings
- ⚠️Limited human data
- ⚠️Exercise synergy important
- ⚠️Emerging research area